The National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) is pleased to announce Project Call 9.1 for technology and workforce development projects. NIIMBL intends to steward up to $8 million in new project activities, which include NIIMBL funding and co-investment from project participants. These investments will support innovative projects that will advance U.S. biopharmaceutical manufacturing. The concept submission deadline is September 16, 2025. Submitters must be NIIMBL members.
Technical concept submissions must focus on platforms and advanced technologies to help the industry address an expanding portfolio of products. Areas of need include product-agnostic analytical technologies, flexible manufacturing platforms, and technologies for better process reliability. The priority technical topic areas for Project Call 9.1 are:
- Real-Time Monitoring and Advanced Process Analytics for In-Process Control
- Integrated Modeling and Control Strategies Linking Upstream, Downstream, and Cell Line Development
- Novel Protein Expression Platforms for Complex and Next-Generation Biotherapeutics
- Digital and Automation Platforms to Enhance Downstream Development and Filtration Scalability
- Advanced AI/ML-Driven Strategies for Biopharmaceutical Process Modeling and Optimization
Workforce development concept submissions must address key needs within the domestic biopharmaceutical industrial base in six specific topic areas:
- Stimulate Knowledge and Interest in Biopharma Manufacturing Careers
- Accelerate Career and Leadership Advancement in Biopharma Manufacturing
- Build an AI-Ready Biopharmaceutical Manufacturing Workforce
- Pilot Lower-Cost Options for Biopharmaceutical Manufacturing Education
- Catalyze Cross-Regional Workforce Development Partnerships
- Build a Future Biopharma Workforce Through Cross-Sector Pathways